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Analysis of human fluid proteomic studies related to aging and frailty

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Zenodo2025-08-13 更新2026-05-26 收录
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The first database includes results from a systematic review of proteomic studies investigating frailty- and age-related changes in biological fluids (PROSPERO ID CRD42024588547). All statistical outcomes from the included studies were consolidated after removing duplicates and applying Benjamini-Hochberg correction for multiple testing. The datasets include: Proteins identified in age-related studies Proteins identified in frailty-related studies Proteins commonly identified in age-related studies. Proteins commonly identified in frailty-related studies. Proteins shared between the two previous datasets, present in at least two age-related studies and two frailty-related studies. The second database includes results from Biological Process in two softwares: STRING and Reactome. These datasets were generated from the proteins extracted in the previous datasets. The datasets include: Results from biological process of STRING for proteins commonly identified in frailty-related studies. Results from biological process of STRING for proteins commonly identified in age-related studies. Results from biological process of STRING for proteins shared between the two previous datasets, present in at least two age-related studies and two frailty-related studies. Results from pathway analysis of Reactome for proteins commonly identified in frailty-related studies. Results from pathway analysis of Reactome for proteins commonly identified in age-related studies. Results from pathway analysis of Reactome for proteins shared between the two previous datasets, present in at least two age-related studies and two frailty-related studies.

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Zenodo
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2025-08-13
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