Observing unfolding and proteolysis of a model protein in real-time: a time-r...

The specific recognition, unfolding and degradation of faulty proteins is an essential process in any living cell in order to guaranteeprotein homeostasis and keep the proteome...异常蛋白质的特异性识别、解折叠与降解，是所有活细胞中保障蛋白质稳态（protein homeostasis）并维持蛋白质组（proteome）……的关键过程。