Locating the Cyclopentano Cousins of the Cucurbit[n]uril Family

The synthesis of the first family of fully substituted
cucurbit­[n]­uril is discussed, and the structural
features of precursor
glycolurils are highlighted in their importance to achieving higher
homologues. The members of the family, where n =
5–7, have been fully characterized, and increased binding affinities
have been identified for dioxane in CyP6Q­[6] and adamantyl
NH3+ in CyP7Q­[7]. A higher homologue
is indicated but not conclusively identified.

本论文探讨了首个全取代型葫芦脲家族的合成，并着重强调了前驱物甘油脲的结构特征，其在实现更高同系物方面的关键作用。该家族成员（n=5-7）已得到全面表征，并在CyP6Q[6]中的二氧六烷和CyP7Q[7]中的金刚基NH3+中识别出增强的亲和力。指示了更高同系物的存在，但尚未得到确切的鉴定。