Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT

Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT Descriptor: CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... Authors: Sun, P, Chen, X, Ding, J. Deposit date: 2022-09-01 Release date: 2022-11-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.506 Å) Cite: Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022