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HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphate ternary complex

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphate ternary complex Descriptor: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... Authors: Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. Deposit date: 2018-10-15 Release date: 2019-01-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.598 Å) Cite: Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors. Biochem. Biophys. Res. Commun., 509, 2019
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2018-10-15
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