Clinicopathological features of 19 DLBCL with a serum monoclonal IgM protein.

CNS1: Central nervous system involvement at diagnosis or during relapse progression. COO2: Cell of Origin defined by the Hans algorithm. IgM-I3: heavy chain IgM expression assessed by immunohistochemistry. MYC-I4: MYC protein expression by immunohistochemistry. BCL2-I5: BCL2 protein expression by immunohistochemistry. MYC-f6: MYC gene translocation by FISH analysis. BCL2-f7: BCL2 gene translocation by FISH analysis, carried out by both IGH/BCL2 and BCL2 break apart probes. BCL6-f8: BCL6 gene translocation by FISH analysis. MYD889: MYD88 gene analyzed for L265P mutation. FUP10: Follow-up. NE11: Not evaluable. NT12: Not translocated. T13: Translocated. CCR114:1st Continuous complete remission. CCR215: 2nd Continuous complete remission. WT16: wild type.