CCL22 mutations in chronic lymphoproliferative disorder of NK cells (CLPD-NK)
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https://www.ncbi.nlm.nih.gov/sra/SRP299479
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资源简介：
We engrafted empty vector, wild type CCL22, and Pro79Arg-CCL22 mutant-expressing NK-92 cells into NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(IL15)1Sz/SzJ mice to assess in vivo function of detected CCL22 mutations. Engrafted Pro79Arg NK-92 cells recapitulated the phenotype of CLPD-NK patients with CCL22 mutations. Overall design: 3 replicates of wild type, empty vector and CCL22-P79R mutant infected NK-92 cell line
创建时间：
2022-01-21
