Impact of plastic-related chemicals on emotional and behavioral health in children from Poland

This research is funded by the National Science Centre, Poland (Grant No. 2011/01/B/NZ7/06462; No. 2014/15/B/NZ7/00998 and No. 2021/41/B/NZ7/04341)The aim of the study was to evaluate the cross-sectional association between childhood exposure to phthalates and non-phthalate plasticizers as well as bisphenols and behavioral outcomes in the REPRO_PL cohort (Poland). Behavioral assessments were performed at the age of 7-9 years by parents using the Strengths and Difficulties Questionnaire (SDQ). HPLC-MS/MS was used for the quantification of BPA and 21 phthalate metabolites corresponding to 11 phthalate compounds (n = 400) and their replacement alternatives BPF, BPS, three metabolites of diethylhexyl terephthalate (DEHTP) and three metabolites of di-isononyl-cyclohexane-1,2-dicarboxylate (DINCH) (n = 150).The attached files contain data on concentrations (in µg/L) of metabolites of phthalate and non-phthalate plasticizers as well as bisphenols in 7–9-year-old children from Poland (n = 400 for phthalate metabolites and BPA; n = 150 for DINCH and DEHTP metabolites and BPF). Additionally, a file containing data on behavioral outcomes is provided.