Assess the ability of disulfiram to inhibit NET formation and improve disease outcome in a Syrian hamster model of COVID-19. RNA sequencing was performed Golden Syrian hamster lung inoculated with SAR
The emergence of resistance to various antibiotics in pneumococci leaves the glycopeptides as the only antibiotics against which pneumococci have no resistance mechanism. This situation has led to a r
Percentage of relapsing mice and bacterial burden in mice vaccinated SC or IN with MVATG18598 or empty vector, MVATGN33.1, during or after antibiotic regimen.
aColony forming units per g of kidneys (experiments 1–4) or lungs (experiment 5); values calculated on 3 mice.bTwo tailed Fisher's exact test.cA172 Live.dIntramuscular.ePfHeat killed A172.