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Parental (F0) compared to MSC educated (F2) prostate cancer cell lines

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Our studies demonstrated that bone marrow derived mesenchymal stromal cells (MSCs) drive the emergence of an apoptosis resistant population of prostate cancer cells that are also cross resistant to chemotherapy such as docetaxel. The goals of this RNAQuant study was to determine differential gene expression between the naïve and MSC educated prostate cancer cells in order to better understand the mechanisms underlying apoptosis resistance.

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