Sdr16c5

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; all-trans-retinol dehydrogenase (NAD+) activity; and transcription corepressor activity. Predicted to be involved in keratinocyte proliferation; negative regulation of macromolecule biosynthetic process; and retinoid metabolic process. Predicted to be located in chromatin; endoplasmic reticulum membrane; and nucleus. Predicted to be part of transcription repressor complex. Predicted to be active in lipid droplet. Predicted to colocalize with endoplasmic reticulum and plasma membrane. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Nov 2024]

预测具有RNA聚合酶II特异性DNA结合转录因子结合活性；全反式视黄醇脱氢酶（NAD+）活性；以及转录共抑制活性。预测参与角质形成细胞的增殖；大分子生物合成过程的负调控；以及视黄醇代谢过程。预测定位于染色质；内质网膜；以及细胞核。预测为转录抑制复合体的一部分。预测在脂滴中活性。预测与内质网和质膜共定位。与人类SDR16C5（短链脱氢酶/还原酶家族16C成员5）同源。[由基因组资源联盟提供，2024年11月]