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TFA-Mediated Tandem Friedel−Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/TFA_Mediated_Tandem_Friedel_Crafts_Alkylation_Cyclization_Hydrogen_Transfer_Process_for_the_Synthesis_of_Flavylium_Compounds/2972869
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资源简介:
The tandem reaction of phenols and chalcones in refluxing TFA gave the flavylium species of 2-hydroxy-2-phenyl-2H-chromenes in moderate to good isolated yields. The reaction was proposed to involve a tandem transformation of Friedel−Crafts alkylation, dehydrative cyclization, intermolecular hydrogen transfer, and hydration. As a multifunctional catalyst, TFA mediated the processes efficiently and cleanly.
创建时间:
2016-06-03
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