Faah
收藏rgd.mcw.edu2025-03-26 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=62100
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资源简介：
Enables monoacylglycerol lipase activity. Involved in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. Is active in glutamatergic synapse. Is expressed in several structures, including brain; ganglia; gut; olfactory epithelium; and renal calyx. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Orthologous to human FAAH (fatty acid amide hydrolase). [provided by Alliance of Genome Resources, Nov 2024]
该基因激活单酰甘油酯脂肪酶活性，参与调节由内源大麻素介导的跨突触信号传导，调节突触传递。在谷氨酸能突触中发挥活性。表达于多个结构中，包括大脑、神经节、肠道、嗅上皮和肾盂。该基因的人源同源基因与肥胖和物质相关疾病有关。与人源脂肪酸酰胺水解酶（FAAH）同源。[由基因组资源联盟提供，2024年11月]
提供机构：
Rat Genome Database
