Structure of Helicobacter pylori Type II Dehydroquinase with a new carbasugar-thiophene inhibitor.
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Structure of Helicobacter pylori Type II Dehydroquinase with a new carbasugar-thiophene inhibitor. Descriptor: (1R,4S,5R)-1,4,5-trihydroxy-3-[(5-methyl-1-benzothiophen-2-yl)methoxy]cyclohex-2-ene-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE Authors: Otero, J.M, Guardado-Calvo, P, Llamas-Saiz, A.L, Prazeres, V.F.V, Tizon, L, Castedo, L, Lamb, H, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. Deposit date: 2009-06-17 Release date: 2009-11-24 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues. J. Med. Chem., 53, 2010
创建时间：
2009-06-17
