The effect of pH change of oxyteracycline solutions on the on inhibition of bioluminescence of Vibrio fischeri (Microtox)

In this study attempt was also made to determine whether a pH change of the sample containing oxyteracycline solutions affects the total toxicity of the sample using the Microtox®
As reported by Kudlak B, Wieczerzak M, Yotova G, Tsakovski S, Simeonov V, Namieśnik J (2016) Environmental risk assessment of Polish wastewater treatment plant activity. Chemosphere 160:181-188. https://doi.org/10.1016/j.chemosphere.2016.06.086), environmental water samples (collected from numerous locations in Poland) had pH values ranging from 4.93 to 8.15, with an average value of 7.15 (Kudłak et al. 2016). Therefore, for this purpose, solutions of oxyteracycline were subjected to pH adjustments with concentrated HCl or NaOH. The solutions were adjusted to seven different pH values ranging from 5.5 to 8.5, and the pH was measured with a pH meter.  Subsequently followed the microtox protocol as described in the Wieczerzak M., Kudłak B. an Namieśnik J., (2016)  Study of the effect of residues of pharmaceuticals on the environment on the example of bioassay Microtox®. Monatshefte für Chemie - Chemical Monthly Volume 147, pages 1455–1460  https://doi.org/10.1007/s00706-016-1782-y

Studies were conducted between 2015.These results are part of the manuscript published in Monatshefte für Chemie - Chemical Monthly
https://doi.org/10.1007/s00706-016-1782-y