Parameters of MutS binding to DNA, ATP hydrolysis and nucleotide exchange in ATPase domain of protein.

aVariable nucleotide pair.bThe ratio of v0 of ATP hydrolysis by MutS in the absence or in the presence of duplexes I–IV to v0 of ATP hydrolysis by MutS in the absence of DNA.cThe ratio of rate constant of mant-ADP dissociation from its complex with MutS (koffmant-ADP) in the absence or in the presence of duplexes I–IV to koffmant-ADP in the absence of DNA.The error of the mean indicates a SEM.