Structure of KLHDC2 bound to SJ46418

Structure of KLHDC2 bound to SJ46418 Descriptor: COBALT HEXAMMINE(III), Kelch domain-containing protein 2, N-({2-[8-(2-methoxyethoxy)naphthalen-2-yl]-1,3-thiazol-4-yl}acetyl)glycine Authors: Scott, D.C, Dharuman, S, Griffith, E, Chai, S.C, Ronnebaum, J, King, M.T, Tangallapally, R, Lee, C, Gee, C.T, Lee, H.W, Ochoada, J, Miller, D.J, Jayasinghe, T, Paulo, J.A, Elledge, S.J, Harper, J.W, Chen, T, Lee, R.E, Schulman, B.A. Deposit date: 2024-04-08 Release date: 2024-11-06 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2. Nat Commun, 15, 2024