Earliest observation of the tetracycline destructase tet(X3)
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA845765
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资源简介:
Tigecycline is an antibiotic of last resort for infections with carbapenem-resistant Acinetobacter baumannii. Plasmids harboring variants of the tetracycline destructase gene tetX promote rising tigecycline resistance rates. We report the earliest observation of tet(X3) in a clinical strain predating tigecycline’s commercialization, suggesting selective pressures other than tigecycline contributed to its emergence.
创建时间:
2022-06-03



