Crystal structure of HCV NS5B polymerase in complex with COMPOUND 29
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Crystal structure of HCV NS5B polymerase in complex with COMPOUND 29 Descriptor: 1-(2,4-difluorobenzyl)-6-{[3-(trifluoromethyl)pyridin-2-yl]oxy}quinazolin-4(1H)-one, GLYCEROL, Genome polyprotein, ... Authors: Coulombe, R. Deposit date: 2013-03-08 Release date: 2013-06-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype. Bioorg.Med.Chem.Lett., 23, 2013
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2013-03-08
