New Chiral Building Blocks from Tetrabromocyclopropene and Furan
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https://figshare.com/articles/dataset/New_Chiral_Building_Blocks_from_Tetrabromocyclopropene_and_Furan/3322855
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资源简介：
The cyclocondensation of tetrabromocyclopropene
and furan leads directly to a halogenated oxabicyclo[3.2.1]octadiene derivative. Over the past several years, we have
utilized these compounds as intermediates for natural
product synthesis. Herein, we describe the preparation of
nonracemic dibromoenone building blocks from the racemic
cycloadduct. Conversion of the adduct to a mixture of
tartrate-derived ketals followed by separation of the diastereomers and hydrolysis allows for the formation of novel
chiral synthons with either absolute configuration.
创建时间：
2016-05-06
