Structure of human MTH1 in complex with TH588
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Structure of human MTH1 in complex with TH588 Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION Authors: Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. Deposit date: 2013-10-04 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
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2013-10-04
