Performed using data from The Cancer Genome Atlas, listed in order of log2 fold change. The top 10 upregulated and downregulated genes are shown. Log2 FC, log2 fold-change in gene expression for USC G
The examples in the table are selected based on that the genes have a mutant frequency greater than 40 in the COSMIC database to show the estimation for the common cases. Due to the limited space, the
Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that
BackgroundSarcomatoid hepatocellular carcinoma (SHC) is a rare epithelial malignancy with high invasiveness and poor prognosis. However, the molecular characteristics and main driver genes for SHC hav