V1V2-specific monoclonal antibodies from RV144 activate complement.

Figshare2017-07-05 更新2026-04-29 收录

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https://figshare.com/articles/dataset/V1V2-specific_monoclonal_antibodies_from_RV144_activate_complement_/5176219 数据链接链接失效反馈

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V1V2-specific monoclonal antibodies from RV144 activate complement.

创建时间：

2017-07-05

Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk

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Using specimens from a phase 1b trial of the RV144 regimen in HIV-1-uninfected South Africans (HVTN 097), we profiled innate responses to the first ALVAC-HIV immunization. PBMC transcriptional respons

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Transcriptomic profiling of RV144 trial participants after vaccination with ALVAC-HIV and AIDSVAX B/E. [rv144]

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The RV144 clinical trial evaluated the efficacy of a vaccine regimen that included ALVAC-HIV prime and AIDSVAX boost in preventing HIV-1 acquisition. The vaccine reduced the risk of HIV-1 acquisition

NIAID Data Ecosystem70

HVTN 505 Antibody and T-Cell Immune Correlates of Risk (2018 JID)

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This dataset contains data through 07 Nov 2014 based on data frozen on 14 Nov 2014.

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BackgroundAntigen processing involves many proteolytic enzymes such as proteasomes and cathepsins. The processed antigen is then presented on the cell surface bound to either MHC class I or class II m

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Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials

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The interferon gamma, enzyme-linked immunospot (IFN-γ ELISpot) assay is widely used to identify viral antigen-specific T cells is frequently employed to quantify T cell responses in HIV vaccine studie

NIAID Data Ecosystem50

V1V2-specific monoclonal antibodies from RV144 activate complement.

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