Transcriptomics analysis of the effects of electrical stimulation on rat denervated gastrocnemius muscle. Transcriptomics analysis of the effects of electrical stimulation on rat denervated gastrocnemius muscle

We report the application of RNA sequencing technology for transcriptomics analysis of the effects of electrical stimulation on rat denervated gastrocnemius muscle. Muscle samples were selected for gene expression analyses，corresponding to the following categories: Sham operation rats, (SHAM, n = 3), sciatic nerve injury rats (DN, n = 3), and sciatic nerve injury with electrical stimulation (DN-SM, n = 3). A total of 14,334 genes (DEGs) were detected in this study. Overall design: Rat gastrocnemius muscle mRNA profiles of SHAM, DN and DN-SM were generated by deep sequencing, using BGISEQ-500.