Nanoparticle-mediated Targeting of the Fusion Gene RUNX1/ETO in t(8;21)-positive Acute Myeloid Leukemia [CUT&RUN]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217110
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资源简介:
To investigate the therapeutic potential of targeting RUNX1/ETO with lipid nanoparticles encapsulating chemically modefied siRNA. Epegnomic profiling was performing on cells lines after lipid nanoparticles in vitro. Comparative epegnomic profiling of RUNX1/ETO, RUNX1 and CEBFB for Kasumi-1 and KSNO-1 cells from in vitro treatment with active siRNA against RUNX1/ETO (LNP/siRE-mod, KD) and control siRNA (LNP/siMM-mod, Ctrl).
创建时间:
2025-07-18



