Sex differences and effect of testosterone on the transcriptome in brain regions underlying quail sexual behavior

To understand the sex differences in brain function that underlie sex differences in behavior we measured the transcriptome of POM, VMN and TnA of adult quail of both sexes either left gonadally intact or gonadectomized and treated with testosterone. Gonadectomy and testosterone-treated groups allowed us to distinguish a suite of genes whose expression is sensitive to testosterone and a suite of genes that are not, the magnitude and pattern of which differs by sex and nucleus. Overall design: differential expression analysis in POM, TnA and VMN between adult T-treated and intact male and female quail