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EMT-associated network collapse induced by YWHAG deficiency leads to oxidative cell death and prevents metastasis.

NIAID Data Ecosystem2026-05-01 收录

EMT分子机制

肿瘤转移抑制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE204929 数据链接链接失效反馈

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资源简介：

Transcriptomics of MKN74 and MKN74YWHAG cells undergoing EMT. Inducing EMT with DMOG and TGFβ in MKN74 and MKN74YWHAG cells

应用场景：

创建时间：

2023-11-09

药物重定向

肿瘤转移抑制

Diltiazem and glibenclamide are commonly used hypotensive and antidiabetic drugs. This study reports the discovery of the potential antitumor and antimetastatic effects of these two drugs using a stru

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Additional file 25 of Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells

EMT分子机制

功能基因组分析

Additional file 25:. Supplementary File S5. GO term enrichment analysis between MKL1 ΔN200 and MKL1 ΔC301. The GO analysis was performed with differentially transcribed, differentially translated and

NIAID Data Ecosystem30

PTEN? suppresses tumor metastasis through regulation of filopodia formation

肿瘤转移抑制

PTEN基因功能

PTEN is one of the most frequently mutated genes in malignancies and acts as a powerful tumor suppressor. Tumorigenesis is involved in multiple and complex processes including initiation, invasion, an

NIAID Data Ecosystem10

Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR-gamma activation

结直肠癌免疫治疗预后

肿瘤转移抑制

Tumor metastasis and lack of NKG2D ligand (NKG2DL) expression are associated with poor prognosis in patients with colon cancer. Here we found that spironolactone (SPIR), an FDA-approved diuretic drug

NIAID Data Ecosystem30

Attenuated RORC Expression in the Presence of EMT Progression in Somatotroph Adenomas following Treatment with Somatostatin Analogs Is Associated with Poor Clinical Recovery

垂体腺瘤

EMT分子机制

Somatostatin analogs (SA) have been established as the first line medical treatment for acromegaly, but following long-term treatment, SA normalizes GH and IGF-I levels in only 40–60% of patients. The

Figshare2016-01-18 更新30

EMT-associated network collapse induced by YWHAG deficiency leads to oxidative cell death and prevents metastasis.

资源简介：

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