Disrupted transcripitonal network in ΔNp63 AEC tissue model
收藏官方服务:
资源简介:
Disrupted transcripitonal network in ΔNp63 AEC tissue model
应用场景:
创建时间:
2012-06-17
相关数据集
BALB/C小鼠肝上皮细胞
该细胞由正常肝上皮细胞BNLCL.2经甲基胆蒽诱导转化而建立,在0.3%的琼脂中可生长,鼠痘病毒阴性。经本库质量控制,该细胞各批次排除外源微生物污染及细胞间的交叉污染,质控合格。
中国科技资源共享网2026-07-14 更新100
Expression data from p63 siRNA in squamous cell lines
p63, a homologue of the tumor suppressor p53, is critical for the development and maintenance of squamous epithelia. p63 is specifically expressed in the basal layers of stratified epithelial tissues
NIAID Data Ecosystem40
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq). Homo sapiens
Tightly controlled gene expression orchestrated by the transcription factor p63 during epithelial differentiation is important for development of epithelial-related structures such as epidermis, limb
NIAID Data Ecosystem20
The Hay Wells Syndrome-Derived TAp63alphaQ540L Mutant Has Impaired Transcriptional and Cell Growth Regulatory Activity
p63 mutations have been associated with several human hereditary disorders characterized by ectodermal dysplasia such as EEC syndrome, ADULT syndrome and AEC syndrome . The location and functional e
NIAID Data Ecosystem60
Expression microarray analysis of HaCaT epidermal keratinocyte treated with AdcaRAS/dnRAS, p53 siRNA, and/or TGF-beta. Homo sapiens
We demonstrate that activation of Ras and TGF-β pathways strengthens the binding of p63 to its genomic sites and modulates the expression of p63 target genes. Our findings support a model of mutual in
NIAID Data Ecosystem30



