Hari Shroff, Catherine G Galbraith, James A. Galbraith, Helen White, Jennifer Gillette, Scott Olenych, Michael W. Davidson, Eric Betzig (2011) CIL:38652, Homo sapiens, fibroblast. CIL. Dataset

This image combines total internal reflection microscopy (TIRF) of mCerulean-actin (blue) with photoactivation localization microscopy (PALM) image of tdEos-vinculin (red) and Dronpa-paxillin (green). Vinculin and paxillin are organized into focal adhesions at the ends of actin bundles. A higher magnification of several adhesion complexes (CIL 38651) clearly shows that vinculin and paxillin are segregated into interlocking microdomains within focal adhesions. Bar is 2 microns. Image made available by Catherine and James Galbraith and corresponds to Figure 5 in PNAS U S A. 2007 Dec 18;104(51):20308-13.

本图像融合了总内反射显微镜（TIRF）对mCerulean-actin（蓝色）的观察结果，以及tdEos-vinculin（红色）和Dronpa-paxillin（绿色）的光激活定位显微镜（PALM）图像。Vinculin与paxillin在肌动蛋白束的末端组织成焦点粘附结构。对数个粘附复合物（CIL 38651）的高倍放大图像清晰显示出，vinculin和paxillin在焦点粘附内部相互嵌套的微区域内分离。图像尺度为2微米。图像由Catherine和James Galbraith提供，并对应于PNAS U S A 2007年12月18日第104卷第51期的第20308-13页中的图5。