Transient inhibition of lysosomal functions potentiates nucleic acid vaccines
收藏NIAID Data Ecosystem2026-05-10 收录
数据链接:
官方服务:
资源简介:
Transient inhibition of lysosomal functions potentiates nucleic acid vaccines
应用场景:
创建时间:
2025-10-30
相关数据集
Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes
Background Lysosomes are acidic organelles that play multiple roles in various cellular oxidative activities such as the oxidative burst during cytotoxic killing. It...
data.gov60
A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body. A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body
The lysosomal function is down-regulated in the white prepupal fat body, resulting in the enlargement of lysosomes in the tissue. The enlargement is blocked by the forced activation of lysosomes by th
NIAID Data Ecosystem50
ATM loss disrupts the autophagy-lysosomal pathway
ATM (ataxia telangiectasia mutated) protein is found associated with multiple organelles including synaptic vesicles, endosomes and lysosomes, often in cooperation with ATR (ataxia telangiectasia and
Taylor & Francis Group2022-10-13 更新20
PA up-regulates the KEGG pathway ‘Lysosome’ in cultured PTECs. PA up-regulates the KEGG pathway ‘Lysosome’ in cultured PTECs
Obesity is a major risk factor for end-stage kidney disease. We previously found that lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in experimental and human obesity-re
NIAID Data Ecosystem60
A lysosomal surveillance response to stress extends healthspan [Exp3]
Lysosomes are cytoplasmic organelles central for the degradation of macromolecules to maintain cellular homeostasis and health. However, how lysosomal activity can be boosted to counteract aging and a
NIAID Data Ecosystem20



