Raw Data of LC-MS on Culex pipiens pallens after selection to three insecticide

Abstract

Background:

Mosquito control based on chemical insecticides is considered as an important element of the current global strategies for the control of mosquito-borne diseases. Unfortunately, the development of insecticide resistance of important vector mosquito species jeopardizes the effectiveness of insecticide-based mosquito control. In contrast to target site resistance, other mechanisms are far from being fully understood.

Methods:

Global protein profiles among cypermethrin-resistant, propoxur-resistant, dimethyl-dichloro-vinyl-phosphate (DDV)-resistant and susceptible strain of Culex pipiens pallens were obtained and proteomic differences were evaluated by using isobaric tags for relative and absolute quantification (iTRAQ) labeling coupled with liquid chromatography/tandem mass spectrometric (LC-MS/MS) analysis.

Results:

A susceptible strain of Cx. pipiens pallens showed elevated resistance levels to after 25 generations of insecticide selection, thro...