Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein involved in pyrimidine biosynthesis. DHODH is a well-validated target for anti-inflammatory and...
This study focused on determining changes in protein levels following inhibition of the mechanistic target of rapamycin using mass spectrometry analysis.
There is currently a drive to establish cell based assay systems of greater human biological and disease relevance through the use of well characterised transformed cell lines, primary cells and compl
Cancer metastasis is a fetal problem that claims life of over 90% of cancer patients. It is hypothesized that cancer stem cells (CSCs) mediate cancer metastasis and such cells are often resistant to c