Chiral Spirooxindole–Butenolide Synthesis through Asymmetric N‑Heterocyclic Carbene-Catalyzed Formal (3 + 2) Annulation of 3‑Bromoenals and Isatins
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https://figshare.com/articles/dataset/Chiral_Spirooxindole_Butenolide_Synthesis_through_Asymmetric_N_Heterocyclic_Carbene_Catalyzed_Formal_3_2_Annulation_of_3_Bromoenals_and_Isatins/2249758
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资源简介:
By
using an N-heterocyclic carbene catalyst bearing a hydroxyl
moiety, the asymmetric formal (3 + 2) cyclization of aryl 3-bromoenals
and isatins was achieved to produce a series of chiral spirooxindole–butenolides
including an alkenyl-substituted compound, which underwent benzannulations
with benzynes to form intriguing spirocyclic scaffolds.
创建时间:
2016-02-16



