Data from: A public database of memory and naive B-cell receptor sequences
收藏DataCite Commons2025-06-01 更新2025-04-09 收录
下载链接:
https://datadryad.org/dataset/doi:10.5061/dryad.35ks2
下载链接
链接失效反馈官方服务:
资源简介:
The vast diversity of B-cell receptors (BCR) and secreted antibodies
enables the recognition of, and response to, a wide range of epitopes, but
this diversity has also limited our understanding of humoral immunity. We
present a public database of more than 37 million unique BCR sequences
from three healthy adult donors that is many fold deeper than any existing
resource, together with a set of online tools designed to facilitate the
visualization and analysis of the annotated data. We estimate the clonal
diversity of the naive and memory B-cell repertoires of healthy
individuals, and provide a set of examples that illustrate the utility of
the database, including several views of the basic properties of
immunoglobulin heavy chain sequences, such as rearrangement length,
subunit usage, and somatic hypermutation positions and dynamics.
提供机构:
Dryad
创建时间:
2016-08-02



