Data on the association of serum glypican-4 with prevalent and future kidney function

The present study included 456 patients who were referred to elective coronary angiography. Serum GPC4 levels were measured with a commercially available ELSIA kit. Glomerular filtration rate (GFR) was estimated (eGFR) using the ‘Chronic Kidney Disease Epidemiology Collaboration’ (CKD-EPI) serum creatinine equation. GFR categories were defined as follows: G1: eGFR≥90 mL/min/1.73 m2; G2: eGFR=60-89 mL/min/1.73 m2; G3a: eGFR=45-59 mL/min/1.73 m2; G3b: eGFR=30-44 mL/min/1.73 m2; G4: eGFR=15-29 mL/min/1.73 m2. Urinary albumin excretion was expressed as ACR in a random morning urine specimen. ACR levels lower than 30 mg/g (category A1) were defined as normal and albuminuria was diagnosed as an ACR of 30 mg/g or greater. CKD was diagnosed in case of eGFR ˂ 60 mL/min/1.73 m2 or albuminuria. After a mean period of 3.5 years, patients were re-invited to undergo a follow-up investigation and kidney function was reassessed. The Table includes baseline characteristics and GPC4 values as well as parameters of kidney function.