Differential receptor expression in the different neuron types.

The kinetics and relative conductance of the different receptors that make up an inhibitory or excitatory synapse onto each neuron results in post-synaptic potentials with equally discernible kinetics. The parameters were chosen based on the corresponding receptor conductance data, if directly available and/or on the characteristics of the resulting PSPs, resulting in a substantial diversity of postsynaptic responses (see Fig 2c). (*) The PSP values reported in this table were obtained by fitting a double exponential function to single, spike-triggered PSPs, recorded at rest for E neurons and at a fixed holding potential of −55 mV for I neurons.