List of datasets and SBSs at G•C base pairs.

Mutation datasets were derived from sixteen cancer genome studies published between 2007 and 2011, five cancer genome studies reported by the ICGC, two datasets of germline pathogenic mutations from HGMD and the “rs” entries (i.e. entries in the dbSNP membership, build 129) from the 1000 Genomes Project. −logP values were obtained from two-tailed t-tests (z-tests for the colorectal cancer datasets) using the NGNN counts from AgilentV2 (EWS) and Duke35 (GWS).1SBS, single base-pair substitutions;2http://dcc.icgc.org/ (JHU, US);3http://dcc.icgc.org/ (RIKEN, JP);4http://dcc.icgc.org/ (NCC, JP);5http://dcc.icgc.org/ (QCMG, AU);6http://dcc.icgc.org/ (OICR, CA);7http://www.biobase-international.com/product/hgmd (HGMD Professional Human Gene Mutation Database, release 2011.3);8http://www.1000genomes.org/ (2011 release).