首页/数据集/Genome-wide KO CRISPR-Cas9 screen on Haploid human embryonic stem cells with TP53 or MLH1 LoF

Genome-wide KO CRISPR-Cas9 screen on Haploid human embryonic stem cells with TP53 or MLH1 LoF

ChEBI2025-12-14 更新2026-07-12 收录

CRISPRi功能基因组学

肿瘤抑制基因干细胞模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-13682 数据链接链接失效反馈

官方服务：

资源简介：

Genome-wide KO CRISPR-Cas9 screen on Haploid human embryonic stem cells with TP53 or MLH1 LoF

应用场景：

创建时间：

2025-12-14

癌细胞耐药性

CRISPRi功能基因组学

Gain and loss of function genome wide CRISPR/Cas9 screens in LGSOC cell lines to identify genes that modulate response to MEK inhibitor trametinib Overall design: LGSOC cells were transduced with geno

NIAID Data Ecosystem80

Developing & Optimizing Acute Myeloid Leukemia Specific Therapeutic Antibodies [CRISPR Screen]. Developing & Optimizing Acute Myeloid Leukemia Specific Therapeutic Antibodies [CRISPR Screen]

抗体药物研发

CRISPRi功能基因组学

Following nearly five decades with few approved therapies for acute myeloid leukemia (AML), the last three years have brought stellar progress with the U.S. Food and Drug Administration approving a nu

NIAID Data Ecosystem50

BT20_24hr_DMSOvERLOTINIB_RNAseq and WHOLE GENOME CRISPR screen

癌症药物机制研究

CRISPRi功能基因组学

BT20 (TNBC) cells were cultured with either DMSO (v/v%) or Erlotinib (10uM) for 24 hours to observe differential expression changes between conditions. CAS-9 expressing BT20 (TNBC) cells were transduc

NIAID Data Ecosystem50

Modulation of gene expression after inducing expression of 14q32 miRNAs by CRISPR activation technology in lung adenocarcinoma

肺腺癌转移机制

CRISPRi功能基因组学

Most lung adenocarcinoma deaths are related to metastases, indicating the necessity of detecting and inhibiting tumor cell dissemination. We have identified that overexpression of miRNAs located on 14

NIAID Data Ecosystem50

Table S2 from Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity

癌症免疫治疗耐药性

CRISPRi功能基因组学

Beta score (sheet1), mapping ratio (sheet2), and essential genes list (sheet3) of CRISPR screens.

Figshare2023-03-01 更新50