Evaluation of the interplay between the ADAR editome and immunotherapy in melanoma
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https://www.ncbi.nlm.nih.gov/sra/SRP293890
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资源简介:
We evaluated the editome of melanoma cell lines generated from patients pre- and post-immunotherapy with immune checkpoint inhibitors by RNAseq. Our results reveal a differential editing in Alu sequences between samples pre-therapy and relapses during therapy with immune checkpoint inhibitors Overall design: RNA sequencing of 12 immunotherapy naive and 11 immunotherapy relapsed unpaired melanoma cell cultures was analysised for gene expression differences and RNA editome differences.
创建时间:
2023-01-11



