Cryo-EM structure of Thromboxane A2 receptor-miniGq protein complex bound to U46619

Cryo-EM structure of Thromboxane A2 receptor-miniGq protein complex bound to U46619 Descriptor: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, CHOLESTEROL, Engineered miniGq, ... Authors: Matzov, D, Krawinski, P, Caffrey, M, Shalev Benami, M. Deposit date: 2024-08-13 Release date: 2025-08-27 Last modified: 2026-04-15 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structural and dynamic insights into agonist recognition and function of the thromboxane A 2 receptor. Nat Commun, 17, 2026