Treatment for Depression Among HIV-Infected Youth

A two-phase study that tested a behavioral intervention to treat depression in HIV-positive adolescents and young adults. Sites were assigned to either the Combination Cognitive Behavioral Therapy (CBT) and Medication Management (MM) (COMB) group or the Treatment as Usual (TAU) group. Phase I was a 24-week pilot test of CBT and MM manuals at sites assigned to the COMB group. Phase II was a feasibility study of the revised CBT and MM manuals. The intervention targeted symptoms of depression, motivation for medical and depression treatment, adherence to medical care, and wellness behaviors.