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SNP weightings used for a PRS of melanoma risk

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NIAID Data Ecosystem2026-05-01 收录
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https://zenodo.org/record/7923162
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The weightings for genetic markers utilized in PRS generation, were derived from independant SNP effect estimate significant at P value < 5e-7) from an adapted iteration of the most recent GWAS meta-analysis on melanoma risk from Landi et al. (Nat Gen, 2020. https://doi.org/10.1038/s41588-020-0611-8). This modified version excluded data from the Brisbane Nevus Morphology Study and the QSkin cohorts, but substantial cohorts such as 23andMe, Inc and UK Biobank were retained. provided are: chromosome, base position (build 37), A1 (effect allele), A2 (non effect allele), P value and odds ratio (OR)
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2023-05-11
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