Single-cell transcription and chromatin accessbility profiles of IDH mutant gliomas. Single-cell transcription and chromatin accessbility profiles of IDH mutant gliomas

we use single cell RNA-seq and ATAC-seq to understand the cell states and epigenetic states of IDH mutant gliomas, including the condition with DNMT1 inhibitor treatment Overall design: Primary IDH mutant glioma samples are collected after surgery and used for the establishment of organoid. Dissociated tumors are used for scRNA-seq and scATA-seq assays from 10x genomics. **'Submitter declares that the raw data will be deposited in dbGaP due to patient privacy concerns.***