Additional file 10: Table S8. of Machine learning classifier for identification of damaging missense mutations exclusive to human mitochondrial DNA-encoded polypeptides

Prediction of validation dataset. Each mutation is described by its phenotype (Mutation type) and numerical values of attributes (feature 1, 2, and 3). The affected polypeptides and amino acid are indicated with the Gene, WT AA, M AA, AA position and Domain columns that refers to gene, wild type and mutant type amino acid, position in the polypeptide and domain. A column with conservation index values for each variant is also included (CI column). Performance of predictors (Mitoclass.1, Provean, Mutpred and PolyPhen-2) shows numerical scores and/or predicted phenotypes. (XLS 292 kb)