首页/数据集/Dose-dependent dual roles of PDGF-BB–PDGFR-? in vascular remodeling and opposing effects of anti-PDGF drug-induced metastasis

Dose-dependent dual roles of PDGF-BB–PDGFR-? in vascular remodeling and opposing effects of anti-PDGF drug-induced metastasis

ChEBI2013-07-22 更新2026-07-21 收录

肿瘤靶向治疗

药物诱导转移机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-46564 数据链接链接失效反馈

官方服务：

资源简介：

Dose-dependent dual roles of PDGF-BB–PDGFR-? in vascular remodeling and opposing effects of anti-PDGF drug-induced metastasis

应用场景：

创建时间：

2013-07-22

肿瘤靶向治疗

药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

NIAID Data Ecosystem90

Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

EGFR突变肺癌耐药机制

肿瘤靶向治疗

Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Figshare2022-11-02 更新30

Preclinical and first-in-human of Purinostat Mesylate, a novel selective HDAC I/IIb inhibitor, in relapsed or refractory multiple myeloma and lymphoma

肿瘤靶向治疗

肿瘤免疫调节

Purinostat Mesylate (PM), a highly selective HDAC I/IIb inhibitor, exhibits excellent antitumor activity in multiple MM and lymphoma cell lines and multiple mouse models, outperforming the pan-HDAC in

NIAID Data Ecosystem20

肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

江苏数据交易所80

Discovery of N ‑Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo‑1 H ‑pyrrolo[2,3‑ c ]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain

蛋白质结构域抑制剂开发

肿瘤靶向治疗

The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under clinical development for oncol

NIAID Data Ecosystem20

Dose-dependent dual roles of PDGF-BB–PDGFR-? in vascular remodeling and opposing effects of anti-PDGF drug-induced metastasis

资源简介：

相关数据集