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Genome-scale functional profiling of cell cycle controls in African trypanosomes

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NIAID Data Ecosystem2026-03-11 收录
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Massive parallel RNAi knockdown was induced in bloodstream-form Trypanosoma brucei. Flow cytometry was then used to divide the perturbed population according to cell cycle phase and RNAi target fragments were deep-sequenced from each pool using RIT-seq such that flow cytometry profiles could be digitally reconstructed at a genomic scale.

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2020-06-22
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