首页/数据集/mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

NIAID Data Ecosystem2026-05-01 收录

肿瘤免疫学

免疫检查点

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213941 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-05-11

肿瘤免疫学

单细胞RNA测序

ProjecTILs human reference atlas of CD8+ tumor-infiltrating T cells, generated by semi-supervised STACAS integration of scRNA-seq datasets spanning 7 cancer types. The dataset is available as a S

DataCite Commons2025-06-01 更新280

肿瘤免疫学

基因调控

Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.

NIAID Data Ecosystem60

Transcriptome of CD8+T-cells from C57BL/6 mice in induced tumor-like conditions along with IL-2 and IL-12.. Transcriptome of CD8+T-cells from C57BL/6 mice in induced tumor-like conditions along with IL-2 and IL-12.

肿瘤免疫学

细胞基因表达

To study differentially expressed genes via RNA seq analysis of CD8+T-cells from C57BL/6 mice splenocytes treated with the four different conditions: IL-2, IL-2 80%TCM, IL-12 and IL-12 80%TCM. (TCM =

NIAID Data Ecosystem60

Additional file 3: of Immune-enrichment of non-small cell lung cancer baseline biopsies for multiplex profiling define prognostic immune checkpoint combinations for patient stratification

非小细胞肺癌

免疫检查点

Refined ICP-interactor annotations on pathways profiles. (XLSX 5574 kb)

DataCite Commons2020-08-27 更新90

Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice

肿瘤免疫学

肿瘤浸润淋巴细胞

CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie

NIAID Data Ecosystem60

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

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