Additional file 6 of Genomic and immune profiling of breast cancer brain metastases

Supplementary Material 6. Gene set enrichment analysis results based on HALLMARK pathways in matched ECT-BrM specimens. Results of gene set enrichment analysis (GSEA) based on HALLMARK pathways in matched FFPE ECT vs FFPE BrM (n = 8 patients), ranked by unadjusted p value. Column names include: Pathway, unique pathway identifier; P, unadjusted enrichment p value; Adjusted P, FDR adjusted p value; ES, enrichment score; NES, enrichment score normalized to mean enrichment of random samples of the same size; Number of genes, number of genes analyzed in the pathway; leadingEdge, HUGO gene symbols of leading-edge genes.