five

Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer’s Disease by Activated Protein C (APC)

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227157
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Activated Protein C is an anti-inflammatory with proven treatment of cardiac and neurological disorders. We studied the transcriptional effects of APC on Alzheimers Disease transgenic mice. Daily i.p. injection of exogenous APC in WT and 5xFAD mice for 5 months. Daily saline injection were given as controls to WT and 5xFAD mice.
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2024-02-25
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