BackgroundAddition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival and served as the first line adjuvant chemotherapy in advanced colorectal cancer (CRC) patients.
Vascular inflammation and myofibroblast activation by TGF-Ã1 are key, yet-to-be-fully-understood pathological processes in fibrosis. Here we report the development of a novel human Tendon-on-a-Chip (
Organoid cultures derived from colorectal cancer (CRC) samples are increasingly used as preclinical models for studying tumor biology and the effects of targeted therapies under conditions capturing i
The responses of individual organoid to different treatments (irradiation, 5-Fu and CPT-11): data for Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer.
